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RAF KINASES
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DeCS
Descriptor
English
:
raf Kinases
Descriptor
Spanish
:
Quinasas raf
Descriptor
Portuguese
:
Quinases raf
Synonyms
English
:
mil-raf Protein Kinases
MIL-RAF Proteins
raf MAP Kinase Kinase Kinases
Tree Number:
D08.811.913.696.620.682.700.559.842
D12.644.360.400.842
D12.776.476.400.842
D12.776.624.664.700.204
Definition
English
:
A
family
of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are
MAP kinase kinase kinases
that play important roles in
SIGNAL TRANSDUCTION.
History Note
English
:
2005
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38718
Unique Identifier:
D048490
Occurrence in VHL
:
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DeCS
CID-10
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